Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NNT All Species: 30.91
Human Site: Y598 Identified Species: 75.56
UniProt: Q13423 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13423 NP_036475.3 1086 113896 Y598 P P E Y N Y L Y L L P A G T F
Chimpanzee Pan troglodytes XP_001134902 1086 113819 Y598 P P E Y N Y L Y L L P A G T F
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536481 1086 113623 Y598 P P E Y N Y L Y L L P A S T F
Cat Felis silvestris
Mouse Mus musculus Q61941 1086 113820 Y598 P P E Y N Y L Y L L P G G T F
Rat Rattus norvegicus NP_001013175 1086 113851 Y598 P P E Y N Y L Y L L P G G T F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508040 959 99995 M501 P T S A F S Q M V T T F G L A
Chicken Gallus gallus
Frog Xenopus laevis NP_001087704 1086 113982 Y598 P P E Y N Y L Y L L P G G G F
Zebra Danio Brachydanio rerio NP_999921 1079 112765 Y594 P P E Y N Y L Y L L P T G V F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_509028 1041 109661 Y579 P L I H S Y A Y L G S S L C C
Sea Urchin Strong. purpuratus NP_001116985 1071 113445 Y582 P P E Y N Y L Y L L P G G I G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 N.A. 96.5 N.A. 93 93 N.A. 79.7 N.A. 86.7 82.3 N.A. N.A. N.A. 60.1 65.1
Protein Similarity: 100 99.8 N.A. 98.4 N.A. 96.2 96 N.A. 84 N.A. 94.1 91.1 N.A. N.A. N.A. 73.3 78.8
P-Site Identity: 100 100 N.A. 93.3 N.A. 93.3 93.3 N.A. 13.3 N.A. 86.6 86.6 N.A. N.A. N.A. 26.6 80
P-Site Similarity: 100 100 N.A. 93.3 N.A. 93.3 93.3 N.A. 20 N.A. 86.6 86.6 N.A. N.A. N.A. 46.6 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 0 10 0 0 0 0 30 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 10 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 80 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 10 0 0 0 0 0 0 10 0 0 70 % F
% Gly: 0 0 0 0 0 0 0 0 0 10 0 40 80 10 10 % G
% His: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 10 0 0 0 0 0 0 0 0 0 0 10 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 10 0 0 0 0 80 0 90 80 0 0 10 10 0 % L
% Met: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 80 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 100 80 0 0 0 0 0 0 0 0 80 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 10 0 10 10 0 0 0 0 10 10 10 0 0 % S
% Thr: 0 10 0 0 0 0 0 0 0 10 10 10 0 50 0 % T
% Val: 0 0 0 0 0 0 0 0 10 0 0 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 80 0 90 0 90 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _